My article on Running Django on Google App Engine had a few bugs at launch. I've since fixed those and just wanted to write a shameless plug for it. App Engine really makes Django fun again. No databases or web servers to worry about. Just upload your code and enjoy the ride.
I built Twiddlee using Django on App Engine and really enjoyed it. It was trivial to write a session engine that used the Datastore API and the integrated support for Python logging in the Admin Console makes it easy to keep track of exceptions. I definitely plan to look to App Engine first for all my future web apps.